Product Description
Mirogabalin Besylate CAS #1138245-21-2 is a white to off-white crystalline powder. It has a specific chemical structure that gives it its distinct pharmacological effects.
It is characterized by its stability under different storage conditions, which is crucial for its use in pharmaceutical formulations. Mirogabalin Besylate CAS #1138245-21-2 is sparingly soluble in water but shows good solubility in certain organic solvents. This solubility profile allows for its incorporation into various drug delivery systems.
The mechanism of action of Mirogabalin Besylate CAS #1138245-21-2 involves binding to specific receptors in the nervous system. It acts as a ligand for the α2δ subunit of voltage-gated calcium channels. By binding to these channels, it reduces the influx of calcium ions into nerve cells. This leads to a decrease in the release of neurotransmitters that are involved in pain transmission.
In particular, Mirogabalin Besylate CAS #1138245-21-2 has been shown to be effective in the treatment of neuropathic pain. Neuropathic pain is a complex and often debilitating condition that can result from a variety of causes, such as diabetes, nerve damage, or viral infections. By targeting the underlying mechanisms of neuropathic pain, Mirogabalin Besylate provides a novel approach to pain management.
Therapeutic Applications
Neuropathic Pain
Mirogabalin Besylate is primarily indicated for the treatment of diabetic peripheral neuropathic pain (DPNP) and postherpetic neuralgia (PHN). These conditions are characterized by chronic pain that can significantly impact the quality of life of patients. Clinical studies have shown that Mirogabalin Besylate can provide significant relief from neuropathic pain, with a favorable side effect profile.
In patients with DPNP, Mirogabalin Besylate has been shown to reduce pain intensity and improve daily functioning. It can also improve sleep quality, which is often disrupted by chronic pain. Similarly, in patients with PHN, Mirogabalin Besylate can provide effective pain relief and improve overall well-being.
Other Potential Applications
In addition to its use in neuropathic pain, Mirogabalin Besylate is being investigated for its potential applications in other neurological disorders. For example, it may have a role in the treatment of fibromyalgia, a condition characterized by widespread pain and tenderness. It is also being studied for its potential use in the treatment of chronic migraine and other headache disorders.
Furthermore, Mirogabalin Besylate may have applications in the field of psychiatry. Some studies have suggested that it may have anxiolytic and antidepressant effects, although further research is needed to confirm these findings.
Clinical Studies
Extensive clinical studies have been conducted to evaluate the safety and efficacy of Mirogabalin Besylate. These studies have involved thousands of patients with neuropathic pain and other conditions. The results of these studies have shown that Mirogabalin Besylate is generally well-tolerated and can provide significant pain relief.
In clinical trials, Mirogabalin Besylate has been compared to placebo and other active treatments. It has been shown to be superior to placebo in reducing pain intensity and improving quality of life. In some cases, it has also been shown to be as effective as or more effective than other established treatments for neuropathic pain.
The safety profile of Mirogabalin Besylate is also favorable. The most common side effects reported in clinical trials include dizziness, somnolence, and peripheral edema. These side effects are generally mild to moderate and can be managed with appropriate dose adjustments or supportive care.
Dosage and Administration
The dosage of Mirogabalin Besylate depends on the patient's condition, age, and other factors. It is usually administered orally in the form of tablets. The starting dose is typically low and may be gradually increased until the desired therapeutic effect is achieved.
Patients should take Mirogabalin Besylate as prescribed by their healthcare provider. It is important to follow the dosing instructions carefully to ensure optimal safety and efficacy. In some cases, dose adjustments may be necessary based on the patient's response to treatment and any side effects experienced.
Mirogabalin besylate Basic information
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Product Name: |
Mirogabalin besylate |
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Synonyms: |
Mirogabalin besylate; Mirogabalin besylat; Mirogabalin Besilate; MIROGABALIN BENZENESULFONIC ACID; ((1R,5S,6S)-6-(carboxymethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)methanaminium benzenesulfonate; [(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0] hept-3-en-6-yl]acetic acid benzenesulfonate; 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid compound with benzenesulfonic acid (1:1); Mirogabalin Besylate 10928 |
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CAS: |
1138245-21-2 |
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MF: |
C18H25NO5S |
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MW: |
367.46 |
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Mirogabalin besylate Chemical Properties
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Solubility |
DMSO: 125 mg/mL (340.17 mM) |
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Form |
Solid |
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Color |
White to off-white |
FAQ
Q1: What payment terms do you accept?
A: We'd like to accept T/T, LC &DP ect.
Q2: How long will it take to ready the good?
A: It is our regular products, we have ready stocks for it normally, if have not stock available, it will takes two weeks for production.
Q3: what specification you supply?
A: We are the manufacturer of the Heparin sodium,We can provide Heparin sodium crude and Heparin sodium according to customer requirement. Our regular specification is BP/USP/IH.
Q4: Can I get a sample?
A: Sure, please sent your sample request to email: eric@huarongpharma.com. We shall handle your request accordingly.
Q5: What is your MOQ?
A: Depend on client's demand, we can arrange small size packing for our customer accordingly.
Q6: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
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