Product Introduction

Plecanatide (CAS No. 467426-54-6) is a synthetic 16-amino acid peptide analog of uroguanylin that acts as a guanylate cyclase-C (GC-C) agonist. By activating the GC-C receptor in the intestinal epithelium, Plecanatide increases cyclic GMP (cGMP) levels, which stimulates intestinal fluid secretion and accelerates transit. Clinically, Plecanatide is used for the treatment of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). Our Plecanatide is synthesized via advanced solid-phase peptide synthesis (SPPS) and purified using HPLC, ensuring high purity, stability, and batch-to-batch consistency suitable for pharmaceutical research and biomedical applications.

Product Parameters (Specification)

Parameter	Specification
Product Name	Plecanatide
CAS No.	467426-54-6
Molecular Formula	C₇₉H₁₁₆N₂₂O₂₄S₂
Molecular Weight	~1960.5 g/mol
Appearance	White to off-white lyophilized powder
Purity (HPLC)	≥98%
Storage	Store at -20°C, protected from light and moisture
Shelf Life	2 years under proper storage conditions

Product Features and Applications

High-purity peptide synthesized using SPPS technology.
GC-C receptor agonist for promoting intestinal fluid secretion.
Clinically used in the treatment of chronic idiopathic constipation (CIC) and IBS-C.
Suitable for pharmaceutical research, drug development, and reference standard studies.
Applicable for gastrointestinal physiology studies, receptor-binding research, and preclinical pharmacology.

Production Details

Plecanatide is produced in GMP-compliant facilities using SPPS followed by HPLC purification and lyophilization. Each batch undergoes rigorous analytical testing including HPLC, MS, amino acid sequencing, optical rotation, moisture content, and solvent residue to ensure identity, purity, and consistency.

Product Qualification

Our manufacturing facilities are ISO9001 and GMP certified. All peptide products are provided with comprehensive documentation including Certificate of Analysis (COA), MSDS, and analytical data. Third-party testing reports are available upon request.

Delivery, Shipping, and Service

Packaging

1mg, 5mg, 10mg, or customized sizes upon request.

Lead Time

Typically 3–5 business days after order confirmation.

Shipping

Express delivery via DHL, FedEx, or UPS with cold-chain protection.

Customer Service

Dedicated technical and after-sales support team available 24/7.

FAQ

Q1: Is Plecanatide for human use?

A: For research and pharmaceutical manufacturing use only, not for direct human administration.

Q2: How should Plecanatide be stored?

A: Keep in a tightly sealed vial at -20°C, protected from moisture and light.

Q3: Can analytical data be provided?

A: Yes, COA, HPLC, and MS data accompany each batch shipment.

Latest News

We continuously invest in R&D for peptide synthesis and formulation technologies, ensuring the highest quality standards for our pharmaceutical-grade peptides. For more peptide innovations, please visit our official website.

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