Flumequine (CAS No.: 42835-25-6) - Broad-Spectrum Quinolone Antibacterial for Veterinary Use

As a professional supplier of veterinary-grade antibacterial active ingredients, we provide high-purity Flumequine that strictly complies with global veterinary pharmacopoeia standards (e.g., EP Vet, USP Vet, CP Vet). A first-generation quinolone antibacterial, it is exclusively designed for veterinary medicine, delivering targeted efficacy against gram-negative and certain gram-positive bacteria-critical for preventing and treating bacterial infections in livestock, poultry, and aquaculture.

Product Basic Information

Product Core Functions & Applications

Flumequine exerts its antibacterial effect by inhibiting bacterial DNA gyrase and topoisomerase IV-key enzymes for bacterial DNA replication, transcription, and repair. This mechanism blocks bacterial proliferation, making it highly effective against susceptible pathogens in veterinary practice (no human pharmaceutical application):

1. Livestock (Pigs, Cattle, Sheep)

Gastrointestinal Infections: Treats and prevents bacterial diarrhea in pigs (e.g., Escherichia coli-induced post-weaning diarrhea, Salmonella enteritis) and cattle (bovine bacterial enteritis caused by Campylobacter spp.), reducing mortality and improving feed conversion efficiency.

Respiratory Infections: Adjuvant treatment for mild-to-moderate bovine respiratory disease (BRD) and porcine respiratory disease complex (PRDC) caused by susceptible gram-negative pathogens (e.g., Pasteurella multocida, Haemophilus parasuis), alleviating cough, nasal discharge, and fever.

Common Dosage Forms: Premixes (mixed with feed) and oral solutions (for individual or group administration).

2. Poultry (Chickens, Ducks, Turkeys)

Enteric & Systemic Infections: Controls avian colibacillosis (caused by E. coli), salmonellosis, and fowl cholera (caused by Pasteurella multocida)-common poultry diseases that cause high flock mortality. It also reduces egg drop syndrome associated with bacterial infections in laying hens.

Administration: Primarily formulated as soluble powders (dissolved in drinking water) for easy group dosing, ensuring uniform drug intake across flocks.

3. Aquaculture (Fish, Shrimp)

Bacterial Diseases: Prevents and treats bacterial septicemia in freshwater and marine fish (e.g., Aeromonas hydrophila in carp, Vibrio anguillarum in salmon) and shrimp (e.g., Vibrio parahaemolyticus in whiteleg shrimp). It effectively reduces skin ulcers, fin rot, and mortality caused by bacterial infections.

Dosage Form: Soluble powders (added to aquaculture water) or feed additives (mixed into fish/shrimp feed), with dosage adjusted based on water temperature and species.

Quality & Safety Assurance

Flumequine's use in food-producing animals requires strict quality control to ensure efficacy, prevent bacterial resistance, and avoid drug residues in animal products:

Raw Material Sourcing: Uses high-purity chemical precursors (e.g., 4-methylaniline, fluoroacetic acid derivatives) and advanced synthesis processes to avoid impurities (e.g., quinolone analogs) that may reduce potency or increase toxicity to target animals.

Production Process: Manufactured in GMP-certified veterinary drug workshops, with strict control over reaction parameters, purification (e.g., recrystallization), and drying to ensure product stability, uniformity, and consistent antibacterial activity.

Testing Protocols: Each batch undergoes comprehensive testing, including:

HPLC analysis for purity, content, and related substance limits (single impurity ≤0.5%, total impurities ≤1.0%).

Heavy metal detection (to meet food safety standards for animal-derived products).

Microbial limit testing (to prevent contamination of feed or water formulations).

Residue marker testing (to validate compliance with maximum residue limits, MRLs).

Safety Reminders:

Withdrawal Periods: Strictly follow species-specific withdrawal periods (e.g., 7 days for pigs, 5 days for chickens, 21 days for fish) to ensure no drug residues in meat, eggs, or aquatic products.

Resistance Prevention: Avoid long-term or overuse; use only for confirmed bacterial infections (not viral diseases) and rotate with other antibacterial classes to reduce resistance development.

Species Restrictions: Not recommended for young animals (e.g., piglets under 3 weeks) or breeding stock unless directed by a veterinarian.

Cooperation & Contact

We supply veterinary-grade Flumequine raw materials for manufacturers of livestock/poultry premixes, soluble powders, and aquaculture formulations, with flexible capacities (from kilogram-level samples to ton-level bulk orders). If you are a veterinary drug enterprise, feed additive manufacturer, or aquaculture supplier, please contact us for:

Detailed veterinary pharmacopoeia compliance documents and residue test reports.

Pricing, bulk discounts, and sample requests.

Technical support (e.g., formulation compatibility, dosage guidance for different species).

Contact Information:

Email: sales@huarongpharma.com

Phone/WhatsApp: +86 13751168070

We adhere to the principles of "veterinary safety, food security" and look forward to establishing long-term, compliant cooperative relationships with global partners in the animal health industry!

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