Oxytetracycline Hydrochloride (CAS No.: 2058-46-0) - Broad-Spectrum Tetracycline Antibiotic for Human & Veterinary Use

As a professional supplier of pharmaceutical and veterinary-grade antibiotics, we provide high-purity Oxytetracycline Hydrochloride that strictly complies with global pharmacopoeia standards (USP, EP, BP, CP). A classic broad-spectrum tetracycline-class antibiotic, it is widely used in human medicine for treating bacterial infections and in veterinary practice for controlling pathogens in livestock, poultry, and aquaculture-offering reliable efficacy and versatile application.

Product Basic Information

Product Core Functions & Applications

Oxytetracycline Hydrochloride exerts its antibacterial effect by inhibiting bacterial protein synthesis-binding to the 30S subunit of bacterial ribosomes, blocking the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, and thus suppressing bacterial growth. Its broad spectrum (active against gram-positive, gram-negative bacteria, and atypical pathogens like rickettsia) makes it applicable in both human pharmaceuticals and veterinary medicine:

1. Human Pharmaceutical Field

Respiratory Tract Infections: Treats community-acquired pneumonia, bronchitis, and pharyngitis caused by susceptible pathogens (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae).

Skin & Soft Tissue Infections: Effective against impetigo, cellulitis, and folliculitis caused by Staphylococcus aureus or Streptococcus pyogenes.

Other Infections: Used for urinary tract infections (UTIs), rickettsial diseases (e.g., typhus, Rocky Mountain spotted fever), and chlamydial infections (in patients allergic to macrolides).

Dosage Forms: Raw material for oral formulations (capsules, tablets, syrups) and topical formulations (ointments, eye drops for bacterial conjunctivitis).

2. Veterinary Field (Veterinary-Grade)

Livestock (Cattle, Pigs, Sheep): Controls bacterial infections such as bovine respiratory disease (BRD), swine dysentery, and sheep chlamydiosis; also used to prevent post-surgical infections and improve feed conversion efficiency in young stock.

Poultry (Chickens, Ducks): Treats avian cholera (caused by Pasteurella multocida), infectious coryza, and mycoplasmosis (chronic respiratory disease, CRD), reducing flock mortality and egg drop.

Aquaculture: Effective against bacterial septicemia in fish (e.g., Aeromonas hydrophila, Vibrio anguillarum) and shrimp (e.g., Vibrio parahaemolyticus), formulated as soluble powders for water administration or premixes for feed.

Common Veterinary Dosage Forms: Premixes, soluble powders, injectables (for severe systemic infections), and oral solutions-designed for easy group or individual dosing.

Quality & Safety Assurance

Oxytetracycline Hydrochloride's broad use requires strict quality control to ensure efficacy, prevent resistance, and avoid residues:

Raw Material Sourcing: Produced via fermentation of Streptomyces rimosus, with strict control over fermentation substrates and conditions to ensure high potency and minimal by-products (e.g., 4-epioxytetracycline).

Production Process: Manufactured in GMP-certified workshops, with advanced purification (e.g., ion-exchange chromatography) and hydrochloride salification processes to remove impurities, endotoxins, and heavy metals. For veterinary-grade products, additional steps ensure compliance with animal feed safety standards.

Testing Protocols: Each batch undergoes comprehensive testing, including:

HPLC analysis for potency, purity, and related substances (e.g., 4-epioxytetracycline ≤5.0%).

Heavy metal (Pb, Hg, Cd) and arsenic detection (to meet food safety requirements for veterinary use).

Microbial limit test (for oral/topical grades) and sterility test (for injectable grades).

Residue testing for veterinary-grade products (to comply with global maximum residue limits, MRLs).

Safety Reminders:

Human Use: Contraindicated in children under 8 years (may cause tooth discoloration and bone growth inhibition) and pregnant/nursing women. May cause photosensitivity-patients should avoid excessive sun exposure.

Veterinary Use: Strictly follow dosage guidelines and withdrawal periods (e.g., 28 days for pigs, 14 days for poultry, 21 days for fish) to prevent drug residues in animal products (meat, milk, eggs). Overuse may lead to bacterial resistance.

Cooperation & Contact

We supply Oxytetracycline Hydrochloride in both pharmaceutical (human oral/topical/injectable grade) and veterinary (premix/soluble powder grade) forms, with flexible capacities (from gram-level R&D samples to ton-level bulk orders). If you are a pharmaceutical manufacturer, veterinary drug enterprise, or aquaculture supplier, please contact us for:

Detailed pharmacopoeia compliance documents, potency certificates, and safety data sheets (SDS).

Pricing, bulk discounts, and sample requests (subject to regulatory approval for human-grade).

Technical support (e.g., formulation compatibility, stability guidance for different dosage forms).

Contact Information:

Email: sales@huarongpharma.com

Phone/WhatsApp: +86 13751168070

We adhere to the principles of "quality first, responsible use" and look forward to establishing compliant, long-term cooperative relationships with global partners in healthcare and animal health!

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