Product Description
Isosorbide mononitrate (ISMN) CAS#16106-20-0 and dinitrate (ISDN) are organic nitrates potentially useful as preload reducing agents in treating heart failure in small animals, however, research and clinical experience demonstrating clinical efficacy are lacking in dogs or cats. Limited research indicates that dogs may require much higher dosages of isosorbide dinitrate to achieve therapeutic effects than do humans.
In humans, isosorbide nitrates are used for treating or preventing angina, treating esophageal spasm, and as an adjunctive treatment in CHF.
Mechanism of Action
Isosorbide mononitrate CAS#16106-20-0 is a vasodilator. It works by relaxing the smooth muscles in blood vessels, leading to dilation of arteries and veins. This results in improved blood flow and reduced workload on the heart. It is primarily used for the treatment and prevention of angina pectoris.
Isosorbide mononitrate CAS#16106-20-0 is an important pharmaceutical ingredient that plays a crucial role in the management of cardiovascular conditions. Its specific properties and mechanism of action make it a valuable tool in the treatment of heart-related disorders.
Isosorbide Mononitrate Basic information
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Product Name |
ISOSORBIDE MONONITRATE |
|
Synonyms |
IS-2-MN; 1,4:3,6-dianhydro-,2-nitrate,d-glucito; 1,4:3,6-dianhydro-d-glucito2-nitrate; 1,4:3,6-dianhydro-d-glucitol2-nitrate; 1,4:3,6-dianhydrosorbitol2-mononitrate; 2-ismn; ISOSORBIDE 2-MONONITRATE; 1,4:3,6-Dianhydro-2-nitro-D-glucitol |
|
CAS |
16106-20-0 |
|
MF |
C6H9NO6 |
|
MW |
191.14 |
|
EINECS |
240-271-4 |
|
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Isosorbide 2-mononitrate Chemical Properties
|
Melting point |
>51.5°C |
|
Boiling point |
326.86°C (rough estimate) |
|
Density |
1.5784 (rough estimate) |
|
Refractive index |
1.4860 (estimate) |
|
Solubility |
Chloroform (Sparingly), Ethanol (Slightly), Methanol (Slightly) |
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