Product Description
Nicergoline CAS#27848-84-6 is a white to off-white crystalline powder. It has a specific chemical structure that gives it its unique pharmacological properties. Nicergoline is moderately soluble in water and shows good solubility in organic solvents.
One of the primary applications of nicergoline CAS#27848-84-6 is in the treatment of cerebrovascular disorders. It helps improve blood circulation in the brain by dilating blood vessels and increasing blood flow. This can be beneficial for patients suffering from conditions such as cerebral atherosclerosis, stroke, and transient ischemic attacks.
Nicergoline CAS#27848-84-6 is also used to treat cognitive impairment and dementia. It may enhance cognitive function by improving blood supply to the brain and promoting neuronal metabolism. This makes it a valuable option for patients with Alzheimer's disease, vascular dementia, and other forms of cognitive decline.
In addition, nicergoline CAS#27848-84-6 has been found to have a positive effect on peripheral circulation. It can be used to treat conditions such as Raynaud's phenomenon and intermittent claudication by improving blood flow to the extremities.
Furthermore, nicergoline CAS#27848-84-6 may have a role in the treatment of certain eye disorders. It has been shown to improve retinal blood flow and may be beneficial for patients with diabetic retinopathy and other retinal vascular diseases.
The use of nicergoline CAS#27848-84-6 offers several benefits. It is generally well-tolerated by patients, with few serious side effects reported. However, as with any medication, there are some considerations. Patients may experience mild side effects such as nausea, dizziness, or headache. In rare cases, more serious side effects such as allergic reactions or liver function abnormalities may occur.
Nicergoline Basic information
|
Product Name |
Nicergoline |
|
Synonyms |
nicergoline Fr.P; 10-Methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinate; Ergoline-8-methanol, 10-methoxy-1,6-dimethyl-, 5-bromo-3-pyridinecarboxylate (ester), (8.beta.)-; 1,6-Dimethyl-8b-(5-bromonicotinoyloxymethyl)-10a-methoxyergoline; Cergodum; Circo-Maren; Dilasenil; Duracebrol |
|
CAS |
27848-84-6 |
|
MF |
C24H26BrN3O3 |
|
MW |
484.39 |
|
EINECS |
248-694-6 |
|
Product Categories |
SPIROPITAN; Miscellaneous Natural Products; Miscellaneous; Adrenoceptor; 27848-84-6 |
Nicergoline Chemical Properties
|
Melting point |
136-138° |
|
Boiling point |
594.4±50.0°C (Predicted) |
|
Density |
1.3558 (rough estimate) |
|
Refractive index |
1.6200 (estimate) |
|
Solubility |
Practically insoluble in water, freely soluble in methylene chloride, soluble in ethanol (96 per cent). |
|
pka |
6.33±0.40 (Predicted) |
|
Form |
Solid |
|
Color |
White to Off-White |
|
Water Solubility |
Soluble in alcohol, chloroform, and acetone. Insoluble in water. |
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