Abaloparatide (CAS: 247062-33-5)

Abaloparatide (CAS: 247062-33-5) is a synthetic analogue of human parathyroid hormone–related protein (PTHrP 1–34). It functions as a selective activator of the PTH1 receptor, stimulating bone formation by increasing osteoblastic activity.
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Description

Product Introduction

 

Abaloparatide (CAS: 247062-33-5) is a synthetic analogue of human parathyroid hormone–related protein (PTHrP 1–34). It functions as a selective activator of the PTH1 receptor, stimulating bone formation by increasing osteoblastic activity. Abaloparatide is widely used for the treatment of osteoporosis in postmenopausal women, offering rapid, significant gains in bone mineral density (BMD) with a favorable safety profile compared to traditional PTH analogues.

 

Product Parameter (Specification)

 

Parameter

Description

Product Name

Abaloparatide

CAS No.

247062-33-5

Molecular Formula

C₁₇₄H₂₉₅N₅₅O₅₁

Molecular Weight

3960.64 g/mol

Purity

≥ 98% (HPLC)

Appearance

White to off-white powder

Solubility

Soluble in water and acetic acid

Storage

Store at −20°C, protected from light and moisture

Grade

Pharmaceutical grade

Shelf Life

2 years under recommended conditions

 

Product Feature and Application

 

  • Synthetic PTHrP analogue designed to promote osteoblast activity and bone formation.
  • Demonstrates rapid improvement in bone density with reduced hypercalcemia risk.
  • Primarily used for treating osteoporosis in postmenopausal women at high fracture risk.
  • Suitable for injectable formulation development and peptide-based drug research.
  • Highly stable and purified peptide ideal for pharmaceutical and preclinical applications.

 

Production Details

 

Abaloparatide is manufactured using advanced solid-phase peptide synthesis (SPPS), followed by multi-step chromatographic purification. Each batch is assessed through HPLC, LC–MS, and peptide mapping techniques to confirm purity, sequence integrity, and bioactivity. Production is conducted under GMP-compliant and ISO 9001-certified quality systems.

 

Product Qualification

 

Our Abaloparatide is produced using pharmaceutical-grade raw materials and validated manufacturing standards. Quality testing includes identity, purity, water content, endotoxin levels, and residual solvents analysis. COA, MSDS, and technical documents are available upon request to support regulatory filings and R&D activities.

 

Delivery, Shipping and Serving

Packaging

1g, 5g, 10g, or customer-specified packaging.

Lead Time

3–5 working days after payment.

Shipping

Global delivery via DHL/FedEx under cold-chain conditions.

Support

Professional technical support, documentation assistance, and after-sales service.

 

FAQ

 

Q1: What is the primary medical use of Abaloparatide?

A1: It is used to treat postmenopausal osteoporosis by stimulating new bone formation.

Q2: How should Abaloparatide be stored?

A2: Store at −20 °C, sealed, and protected from moisture and light. Reconstituted solutions should be used promptly.

Q3: Is GMP documentation available?

A3: Yes, COA, MSDS, and GMP-related documentation can be provided on request.

 

Latest News

 

Abaloparatide is part of our expanding peptide hormone portfolio, which includes Teriparatide, PTH fragments, and other bone-metabolism–related peptides. With advanced synthesis capabilities and strict GMP quality control, our company is committed to supplying high-quality peptide APIs for global pharmaceutical research and therapeutic development.

 

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