Moxidectin CAS#113507-06-5

Moxidectin, with the chemical registry number CAS#113507-06-5, is a potent antiparasitic agent that has gained significant attention in the field of veterinary medicine and animal health.

Moxidectin is a macrocyclic lactone compound that belongs to the milbemycin class of antiparasitic drugs. It has a complex chemical structure consisting of a large lactone ring with several attached functional groups.

In terms of physical properties, moxidectin is a white to off-white crystalline powder. It is sparingly soluble in water but more soluble in organic solvents such as methanol and ethanol. Moxidectin has a high melting point and is stable under normal storage conditions.

Moxidectin acts by interfering with the nervous system of parasites. It binds to specific receptors in the parasite's nerve cells, leading to an increase in the permeability of cell membranes to chloride ions. This results in hyperpolarization of the nerve cells and paralysis of the parasite.

The drug is effective against a wide range of internal and external parasites, including roundworms, hookworms, whipworms, heartworms, and certain types of mites and ticks. Moxidectin has a long duration of action, providing extended protection against parasitic infections.

When administered orally or by injection, moxidectin is rapidly absorbed from the gastrointestinal tract or the site of injection. The drug is then distributed throughout the body, reaching high concentrations in tissues such as the liver, lungs, and kidneys. Moxidectin has a long half-life, which allows for extended periods of activity and reduces the frequency of dosing.

The drug is metabolized in the liver and excreted mainly in the feces. Some metabolites may also be excreted in the urine. The pharmacokinetics of moxidectin can vary depending on factors such as the species of animal, age, weight, and health status.

Moxidectin is generally considered safe and well-tolerated in animals. However, like any drug, it can cause side effects in some individuals. The most common side effects include vomiting, diarrhea, loss of appetite, and lethargy. These side effects are usually mild and self-limiting.

In rare cases, more serious side effects such as allergic reactions, liver toxicity, or neurological disorders may occur. It is important to follow the recommended dosage and administration guidelines to minimize the risk of side effects. Animals with pre-existing liver or kidney disease may require special precautions and closer monitoring when taking moxidectin.

Moxidectin is available in various formulations, including tablets, chewable tablets, topical solutions, and injections. The dosage and administration route depend on the species of animal, the type of parasitic infection being treated, and the weight of the animal.

For oral administration, the drug is typically given as a single dose. For topical applications, the solution is applied to the skin at the back of the neck. Injections are usually given intramuscularly or subcutaneously. It is important to consult a veterinarian for accurate dosing instructions and to ensure the proper use of the drug.

Moxidectin is a highly effective antiparasitic agent that has made a significant contribution to the health and well-being of animals. Its broad spectrum of activity, long duration of action, and relatively safe profile make it a valuable tool in the fight against parasitic infections. With continued research and development, moxidectin and other antiparasitic drugs will continue to improve the quality of life for animals and help ensure the sustainability of the livestock and companion animal industries.

Hot Tags: moxidectin cas#113507-06-5, China moxidectin cas#113507-06-5 manufacturers, suppliers, Veterinary raw materials, Biopharmaceuticals