4 - bromopyridine hydrochloride is a significant chemical compound that finds wide - ranging applications in the fields of pharmaceuticals, agrochemicals, and materials science. As a reliable supplier of 4 - bromopyridine hydrochloride, I am often asked about its melting point. In this blog, I will explore the melting point of 4 - bromopyridine hydrochloride, its influencing factors, and its importance in various industries.
What is 4 - bromopyridine hydrochloride?
4 - bromopyridine hydrochloride is an organic compound with the molecular formula C₅H₄BrN·HCl. It is a white to off - white crystalline powder. The compound is derived from pyridine, a heterocyclic aromatic organic compound. The bromine atom at the 4 - position of the pyridine ring and the hydrochloride salt form give it unique chemical and physical properties.
The Melting Point of 4 - bromopyridine hydrochloride
The melting point of 4 - bromopyridine hydrochloride typically ranges from 270 - 274 °C. This relatively high melting point is due to the strong intermolecular forces present in the compound. The ionic nature of the hydrochloride salt contributes to the formation of strong electrostatic attractions between the ions, which require a significant amount of energy to break during the melting process.
Factors Affecting the Melting Point
- Purity: The purity of 4 - bromopyridine hydrochloride has a direct impact on its melting point. A highly pure sample will have a sharp melting point within the expected range. Impurities can disrupt the regular crystal lattice structure of the compound, causing the melting point to be lower and the melting range to be broader. For example, if there are traces of other brominated pyridines or inorganic salts in the sample, the melting point may deviate from the standard value.
- Crystal Structure: The crystal structure of 4 - bromopyridine hydrochloride can also influence its melting point. Different crystal forms (polymorphs) of the same compound may have different melting points. Polymorphs have different arrangements of molecules in the crystal lattice, which result in different intermolecular forces. Some polymorphs may be more stable than others, and the more stable polymorph usually has a higher melting point.
Importance of Melting Point in Different Industries
Pharmaceutical Industry
In the pharmaceutical industry, the melting point of 4 - bromopyridine hydrochloride is a critical parameter. It is used as an intermediate in the synthesis of various pharmaceutical compounds. For example, it can be used in the synthesis of drugs that target specific biological pathways. The melting point is used as a quality control measure during the manufacturing process. A consistent melting point indicates that the compound has the correct chemical structure and purity, which is essential for ensuring the efficacy and safety of the final pharmaceutical product.
Agrochemical Industry
4 - bromopyridine hydrochloride is also used in the agrochemical industry. It can be a building block for the synthesis of pesticides and herbicides. The melting point of the compound affects its solubility and reactivity during the formulation process. Compounds with the correct melting point are more likely to dissolve uniformly in solvents and react predictably with other chemicals, leading to more effective agrochemical products.
Materials Science
In materials science, 4 - bromopyridine hydrochloride can be used in the synthesis of novel materials with specific properties. The melting point is important for determining the processing conditions of these materials. For example, if the compound is used in the preparation of polymers or composite materials, the melting point helps in deciding the temperature at which the compound can be incorporated into the material matrix.
Comparison with Other Related Compounds
To better understand the melting point of 4 - bromopyridine hydrochloride, it is useful to compare it with other related compounds. For instance, Silver Chloride|CAS 7783 - 90 - 6 has a melting point of 455 °C. The difference in melting points can be attributed to the different chemical structures and intermolecular forces. Silver chloride is an inorganic salt with strong ionic bonds, while 4 - bromopyridine hydrochloride is an organic salt with a combination of ionic and covalent bonds.
Another example is Doramectin CAS#117704 - 25 - 3, which is a veterinary drug. Doramectin has a melting point of around 148 - 150 °C. The lower melting point of Doramectin compared to 4 - bromopyridine hydrochloride is due to its more complex organic structure with weaker intermolecular forces.
Gatifloxacin Mesylate CAS#316819 - 28 - 0 is an antibacterial agent. Its melting point is around 233 - 235 °C. Similar to the other comparisons, the difference in melting points is related to the chemical structure and the types of intermolecular forces present in the compound.
Our Supply of 4 - bromopyridine hydrochloride
As a supplier of 4 - bromopyridine hydrochloride, we are committed to providing high - quality products. We have strict quality control measures in place to ensure that our 4 - bromopyridine hydrochloride has a melting point within the standard range of 270 - 274 °C. Our production process is designed to minimize impurities and produce a consistent crystal structure, resulting in a product with a sharp melting point.
We understand the importance of the melting point for our customers in different industries. Whether you are in the pharmaceutical, agrochemical, or materials science field, our 4 - bromopyridine hydrochloride can meet your specific requirements. We offer various packaging options and can provide technical support to help you with your applications.
Contact Us for Procurement
If you are interested in purchasing 4 - bromopyridine hydrochloride or have any questions about its melting point, properties, or applications, please feel free to contact us. We are ready to discuss your needs and provide you with the best solutions.
References
- "The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals", Merck & Co., Inc.
- "Organic Chemistry" by Paula Yurkanis Bruice.
- Journal articles on the synthesis and properties of 4 - bromopyridine hydrochloride.