Lansoprazole CAS#103577-45-3

Lansoprazole CAS#103577-45-3

Lansoprazole is in a class of drugs called proton pump inhibitors (PPI) which prevent the stomach from producing gastric acid. The other drugs in PPI family include: rabeprazole (Aciphex), omeprazole (Prilosec), pantoprazole (Protonix), esomeprazole (Nexium).
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Description
Product Description

 

Lansoprazole is in a class of drugs called proton pump inhibitors (PPI) which prevent the stomach from producing gastric acid. The other drugs in PPI family include: rabeprazole (Aciphex), omeprazole (Prilosec), pantoprazole (Protonix), esomeprazole (Nexium).

Proton pump inhibitors are used for the treatment of conditions such as ulcers, gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome that are caused by stomach acid. Lansoprazole, like other proton-pump inhibitors, blocks the enzyme in the
wall of the stomach that produces acid. By blocking the enzyme, the production of acid is decreased, and this allows the stomach and esophagus to heal.

Lansoprazole is primarily used for the treatment of various gastrointestinal disorders. One of its main applications is in the management of gastroesophageal reflux disease (GERD). GERD occurs when stomach acid flows back into the esophagus, causing symptoms such as heartburn, acid regurgitation, and chest pain. Lansoprazole works by reducing the production of stomach acid. It does this by inhibiting the proton pump in the stomach lining, which is responsible for secreting acid. By suppressing acid production, Lansoprazole helps to relieve the symptoms of GERD and promote healing of the damaged esophagus.

In addition to GERD, Lansoprazole is also used in the treatment of peptic ulcers. Peptic ulcers are open sores that develop in the lining of the stomach or duodenum. Excessive stomach acid can contribute to the formation and worsening of these ulcers. By reducing acid secretion, Lansoprazole can aid in the healing of peptic ulcers and prevent their recurrence.

Lansoprazole is available in various formulations, including capsules and tablets. It is usually taken orally once a day, although the dosage may vary depending on the specific condition being treated and the individual patient's needs.

This compound has several advantages. It is highly effective in reducing stomach acid production, providing quick relief from symptoms. Lansoprazole is also generally well-tolerated, with few serious side effects. However, like all medications, it may cause some adverse reactions in some individuals, such as headache, diarrhea, or abdominal pain.

 

Lansoprazole Chemical Properties

 

Melting point

178-182°C dec.

Boiling point

555.8±60.0°C (Predicted)

Density

1.50±0.1 g/cm3 (Predicted)

Storage temp.

2-8°C

Solubility

Practically insoluble in water, soluble in anhydrous ethanol, very slightly soluble in acetonitrile.

pka

pKa 2.34±0.37 (Occasionally); 3.53±0.37 (Occasionally); 8.48±0.30 (Occasionally)

Form

Powder

Color

Off-white

 

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