Heparin sodium interacts with other drugs

1. Combining heparin with the following drugs can increase the risk of bleeding: coumarin and its derivatives, aspirin and non-steroidal anti-inflammatory analgesics, dipyridamole, dextran, adrenocortical hormone, adrenocorticotropic hormone, tissue fibrinolysis Zymogen activator, urokinase, streptokinase, etc.
2. The combined use of heparin and drugs such as sodium bicarbonate and sodium lactate to correct acidosis can promote the anticoagulant effect of heparin.
3. Mixed injection of heparin and hyaluronidase can not only reduce the pain of intramuscular injection, but also promote the absorption of heparin. However, heparin can inhibit hyaluronidase activity, so the two should be used temporarily together, and the drugs should not be left for a long time after being mixed.
4. Heparin can interact with insulin receptors, thereby changing the binding and action of insulin.
5. Cannot be used in combination with alkaline drugs.
Note: The above content is only for introduction. The use of drugs must be done in a regular hospital under the guidance of a doctor.